Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003o023 | Oral Communications 3: Environmental and programming effects on reproduction | SRF2016

Paternal low protein diet affects fetal growth, placental development and skeletal formation in mice

Watkins Adam , Sirovica Slobodan , Stokes Ben , Addison Owen , Martin Richard

Human and animal models have demonstrated the importance of maternal gestational diet for fetal growth, placental function and long-term offspring health. However, the impact of paternal diet on offspring development remains under-investigated. We have demonstrated that a paternal low protein diet (LPD 9% protein), programmes elevated offspring weight at birth, adult adiposity, glucose intolerance and cardiovascular dysfunction when compared to offspring from control normal pr...